Dieta sin gluten y sin caseína en los trastornos del espectro autista; perspectivas diferentes / Gluten-free, casein-free diet in autism spectrum disorders; different perspectives

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Rasgos clínicos sugestivos de trastorno del espectro autista como manifestación de sensibilidad al gluten no celíaca / Clinical features suggesting autism spectrum disorder as a manifestation of non-celiac gluten sensitivity

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Del intestino al cerebro..., pasando por el torrente sanguíneo / From gut to brain..., passing through the blood stream

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Leucemia linfoblástica aguda diagnosticada y tratada inicialmente como artritis crónica juvenil / Acute lymphoblastic leukaemia initially diagnosed and treated as chronic juvenile arthritis

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Intoxicación por vitamina D en hijos de inmigrantes latinoamericanos. Serie de 3 casos / Vitamin D intoxication in infants born from Latin-American immigrants. Series of 3 cases

La intoxicación por vitamina D es una causa bien conocida de hipercalcemia infantily puede tener serias consecuencias (renales, cardiacas y neurológicas fundamentalmente). El empleo de suplementos nutricionales enriquecidos con vitaminas, de venta sin receta, conlleva un importante riesgo de que esto ocurra. La clínica de la hipercalcemia es inespecífica y, unida al hecho de que con frecuencia se niega la ingesta de dichos suplementos, el diagnóstico de intoxicación por vitamina D se demora y el número de pruebas complementarias realizadas es amplio. Exponemos una serie de 3 casos de hijos de inmigrantes latinoamericanos que estaban recibiendo suplementos nutricionales traídos de los países de origen de sus padres. Los 3 se presentaron en nuestro centro en un intervalo de 5 meses. Tras el antecedente de un primer caso, el diagnóstico de los 2 siguientes fue más rápido, así como la instauración del tratamiento para la hipercalcemia. Los niveles iniciales de calcio y 25-hidroxivitamina D fueron, respectivamente, para cada caso: 17,9 mg/dl y 504 ng/ml, 14,46 mg/dl y 505 ng/ml, y 14,2 mg/dl y530 ng/ml. Recibieron tratamiento con sueroterapia, furosemida y corticoides, y en uno de los casos con calcitonina subcutánea. La evolución clínica de todos ellos fue óptima, normalizándosela calcemia y la función renal (AU)

Vitamin D intoxication is a well-known cause of hypercalcemia in children and can have serious consequences (renal, cardiac and neurologic mainly). The use of the so-called over the-counter (OTC) supplements involves a high risk in this taking place. The clinical expression of hypercalcaemia is unspecific, and, together with the fact that the administration of such supplements is frequently denied, the diagnosis of vitamin D intoxication is often delayed and the number of complementary tests performed is high. We here-for expose a series of 3 cases all of which are infants born from Latin-American immigrants who were receiving supplements that came from their parents originary countries. All 3 cases were admitted in our hospital within a period of 5 months. After the first preceding case, the diagnosis of the 2 latter ones was performed promptly and so was the instauration of the treatment for hypercalcemia. The initial levels of serum calcium and of 25-hydroxy vitamin D where, respectively for each case: 17.9 mg/dl and 504 ng/ml; 14.46 mg/dl and 505 ng/ml; 14.2 mg/dl and 530 ng/ml. All 3 patients received intravenous treatment with serum, furosemide and corticoids and in one case with subcutaneous calcitonine as well. The clinical outcome was optimal for them all, with normalization of the calcium levels and of the renal function (AU)

[Vitamin D intoxication in infants born from Latin-American immigrants. Series of 3 cases]. / Intoxicación por vitamina D en hijos de inmigrantes latinoamericanos. Serie de 3 casos.

Vitamin D intoxication is a well-known cause of hypercalcemia in children and can have serious consequences (renal, cardiac and neurologic mainly). The use of the so-called over-the-counter (OTC) supplements involves a high risk in this taking place. The clinical expression of hypercalcaemia is unspecific, and, together with the fact that the administration of such supplements is frequently denied, the diagnosis of vitamin D intoxication is often delayed and the number of complementary tests performed is high. We here-for expose a series of 3 cases all of which are infants born from Latin-American immigrants who were receiving supplements that came from their parents originary countries. All 3 cases were admitted in our hospital within a period of 5 months. After the first preceding case, the diagnosis of the 2 latter ones was performed promptly and so was the instauration of the treatment for hypercalcemia. The initial levels of serum calcium and of 25-hydroxy vitamin D where, respectively for each case: 17.9 mg/dl and 504 ng/ml; 14.46 mg/dl and 505 ng/ml; 14.2mg/dl and 530 ng/ml. All 3 patients received intravenous treatment with serum, furosemide and corticoids and in one case with subcutaneous calcitonine as well. The clinical outcome was optimal for them all, with normalization of the calcium levels and of the renal function.